Human Models. Measured Answers. Stated Limits.
Built on New Approach Methodologies (NAMs), ProNAMs is a dedicated biological evaluation partner. We use 3D tissue systems, patient-derived tumor models, and microphysiological systems to answer the specific question your program needs answered, and we state what each dataset can support.
What We Do
Complex models are adopted because they retain physiology that conventional culture discards. That same complexity makes them harder to interrogate and harder to control, which is where the design work has to happen.
We work the other way round. The decision defines the endpoint, the endpoint defines the model, and every dataset is delivered with the applicability domain that governs how far it can be pushed. Where a question sits outside what a platform can answer, we say so at scoping rather than in the final report.
Tissue & Disease Modeling
Human 3D tissue models and microphysiological systems for efficacy, organ-level safety, and mechanism.
- 3D full-thickness skin
- iPSC-derived cardiac MPS
- iPSC-derived hindbrain microtissue & EV screening
Oncology Evaluation
Patient-derived tumor models, tumor–immune co-culture, and native tissue-context studies for modern oncology modalities.
- Patient-derived 3D tumor model
- 3D tumor–immune co-culture
- ALI tumor fragment models for ADC penetration
Enabling Technologies
Making complex models readable, and the environment they sit in controlled. Available standalone, or built into an evaluation study.
- Stable lentiviral transduction of 3D tumor microtissues
- Dynamic perfusion assay configuration services
How We Work
One protocol, one feasibility gate, one client review round. Every data package includes raw data, QC records, and an interpreted report.
Scoping
We learn your program goals, timeline, and the biological questions that matter most to your team.
Design & Quotation
We tailor each study plan with the right model, endpoints, and throughput, ensuring the intended context of use is defined upfront.
Materials & Feasibility
Culture media, matrices, and consumables are sourced from commercial suppliers, with lot numbers and certificates of analysis retained for every study.
Model Build & Release
Our lab constructs and validates models with strict verification thresholds.
Study Execution
Our lab runs the study with rigorous QC checkpoints. You get mid-study updates, not a black box.
Analysis & Reporting
You receive a report with raw data, analysis, and interpretation you can take into your next decision.
Tell us the decision
your data has to support.
We will tell you which model fits, what it can conclude, and where it stops.
Schedule a Consultation